2023年1月27日(金)-28(土)第21回武田科学振興財団生命科学シンポジウム ヒト発生と進化の理解に向けて(Towards Understanding Human Development and Evolution) プログラム

プログラム

第21回武田科学振興財団生命科学シンポジウム

as of January 13, 2023
DAY 1

January 27
2023
09:30Opening Remarks
Mitinori Saitou   Kyoto University/ASHBi
Germ Cells: Genetic and Epigenetic Inheritance
Session1-Part①

Chairperson: Mitinori Saitou
Kyoto University/ASHBi, Japan

09:40S1-1 Poly(UG)-tailed RNAs in Genome Defense and Transgenerational Epigenetic Inheritance
Scott Kennedy
Harvard Medical School, U.S.A.
10:10S1-2  Mammalian epigenetic inheritance at metastable epialleles – Agouti viable yellow revisited
Anne Ferguson-Smith
University of Cambridge, U.K.

Coffee Break (20 min.) 10:40-11:00


Session1-Part②

Chairperson: Anne Ferguson-Smith
University of Cambridge, U.K.

11:00S1-3  Genome Instability in the Human Germline: From Molecular Mechanisms to Reproductive Health
Eva R. Hoffmann
University of Copenhagen, Denmark
11:30S1-4  Mechanism and in vitro reconstitution of mammalian germ-cell development
Mitinori Saitou
Kyoto University/ASHBi, Japan

Lunch (50 min.) 12:00-12:50

Poster Session (65 min. each)
12:50-13:55 / Odd Number
13:55-15:00 / Even Number

Session2-Part①
Human Development In Vivo and In Vitro

Chairperson: Eva R. Hoffmann
University of Copenhagen, Denmark

15:05S2-1  Genomic Insights into Early Human Brain Development, Evolution, and Disease
Arnold Kriegstein
University of California, San Francisco(UCSF), U.S.A.
15:35S2-2  Regulation of neural stem cell fate
Yukiko Gotoh
The University of Tokyo/IRCN, Japan
16:05S2-3  Neural Development in Stem Cell Culture
Mototsugu Eiraku
Kyoto University/ASHBi, Japan

Coffee Break (20 min.) 16:35-16:55

Session2-Part②

Chairperson: Mototsugu Eiraku
Kyoto University/ASHBi, Japan.

16:55S2-4  Discovering cell types, cell dynamics, and cell regulators by single cell transcriptomics
Allon Klein
Harvard Medical School, U.S.A.
17:25S2-5  The understanding of stem cell niche for adult human endoderm-derived organs
Toshiro Sato
Keio University, Japan

Welcome Reception (100 min.) 18:00-19:40

DAY 2

January 28
2023
Session2-Part③
Human Development In Vivo and In Vitro

Chairperson: Tadashi Isa
Kyoto University/ASHBi, Japan

09:00S2-6  Growing organs in vivo: interspecies organogenesis for transplantable organ generation
Hiromitsu Nakauchi
Stanford University, U.S.A.
09:30S2-7  Multicellular coordination in context
Takashi Hiiragi
Hubrecht Institute, Netherland/ASHBi, Japan
10:00S2-8  Towards a (bio)physical basis for morphogenesis
L. Mahadevan
Harvard University, U.S.A.

Coffee Break (20 min.) 10:30-10:50

Session2-Part④

Chairperson: Takashi Hiiragi
Hubrecht Institute, Netherland/ASHBi, Japan

10:50S2-9  Modeling Neurological diseases using Human iPS cell technologies and Genetically Modified Non-human primates
Hideyuki Okano
Keio University, Japan
11:20S2-10  Large-scaled adult brain network plasticity for recovery from spinal cord injury
Tadashi Isa
Kyoto University/ASHBi, Japan
11:50S2-11  Rare begets Common
Bruno Reversade
Institute of Medical Biology, A*STAR, Singapore

Speaker's Photo Session (10 min) 12:20-12:30

Lunch (50 min.) 12:30-13:20

Poster Session -Free Discussion- (45 min.) 13:20-14:05

Session3-Part①
Human Genetics and Evolution

Chairperson: Yukiko Gotoh
The University of Tokyo/IRCN, Japan

14:10S3-1  Dynamics and evolution of human cis-regulatory elements
Yasuhiro Murakawa
Kyoto University/ASHBi, Japan
14:40S3-2  One brain, many genomes: Somatic mutation in human brain
Chris Walsh
Harvard Medical School, U.S.A.

Coffee Break (20 min.) 15:10-15:30


Session3-Part②

Chairperson: Yasuhiro Murakawa
Kyoto University/ASHBi, Japan

15:30S3-3  Deciphering Developmental Disorders
Matthew Hurles
Wellcome Sanger Institute, U.K.
16:00S3-4  A Neandertal Perspective on Recent Human Evolution
Svante Pääbo
Max Planck Institute, Germany

Award Ceremony & Closing Remarks (20 min.) 16:30-16:50